witchlinblue
02-05-2006, 04:17 AM
Sleeping Through Detox Poses Hazards
By Kenneth J. Bender, Pharm.D, M.A.
Psychiatric Times December 2005 Vol. XXIII Issue 14
Anesthesia-assisted opioid withdrawal, offered as quicker and easier than other rapid detoxification methods, was recently found to be comparable on several measures, but with greater risk for life-threatening adverse events. A randomized trial comparing anesthesia-, buprenorphine- (Subutex) and clonidine- (Catapres) assisted heroin detoxification found similarity in withdrawal symptom severity, low rates of inpatient program completion and high proportion of follow-up opioid-positive urine tests (Collins et al., 2005). While no detoxification procedure appeared "painless" or to facilitate program compliance or long-term abstinence, the anesthesia- and buprenorphine-assisted protocols were superior to the clonidine program in facilitating the naltrexone (ReVia) induction to rapidly counter opioid effect.
Read Whole Article (http://www.psychiatrictimes.com/showArticle.jhtml?articleId=175803682)
By Kenneth J. Bender, Pharm.D, M.A.
Psychiatric Times December 2005 Vol. XXIII Issue 14
Anesthesia-assisted opioid withdrawal, offered as quicker and easier than other rapid detoxification methods, was recently found to be comparable on several measures, but with greater risk for life-threatening adverse events. A randomized trial comparing anesthesia-, buprenorphine- (Subutex) and clonidine- (Catapres) assisted heroin detoxification found similarity in withdrawal symptom severity, low rates of inpatient program completion and high proportion of follow-up opioid-positive urine tests (Collins et al., 2005). While no detoxification procedure appeared "painless" or to facilitate program compliance or long-term abstinence, the anesthesia- and buprenorphine-assisted protocols were superior to the clonidine program in facilitating the naltrexone (ReVia) induction to rapidly counter opioid effect.
Read Whole Article (http://www.psychiatrictimes.com/showArticle.jhtml?articleId=175803682)